John Wayne Casserole
Hey there, food lover! Get ready to discover a recipe that’s about to become a staple in your kitchen and a star on your dinner table. I’m talking about a dish that whispers comfort, shouts flavor, and effortlessly brings smiles all around. This John Wayne Casserole isn’t just a meal; it’s a warm hug after a long day, a joyous centerpiece for celebrations, and frankly, a secret weapon in your culinary arsenal. Trust me, you’re going to absolutely adore this one it’s a game-changer!
Why You’ll Love This John Wayne Casserole
This recipe isn’t just about the ingredients; it’s about creating moments. Whether you’re cooking for a casual family dinner, hosting a get-together with friends, or simply indulging in some comforting flavors for yourself, this dish is versatile enough to fit the occasion. Here’s why it’s a favorite:
Versatile
While the classic layers are truly delicious, this casserole is incredibly adaptable! You can swap out the bell peppers for green chilies for more kick, add corn or black beans for extra texture, or even use ground turkey instead of beef. It truly adapts to whatever you’re craving or whatever you have on hand.
Budget-Friendly
Stretch your dollar without compromising on taste! This recipe uses readily available, affordable ingredients that transform into something truly spectacular. It’s proof that delicious, satisfying meals don’t have to break the bank.
Quick and Easy
Life’s busy, and sometimes you need a meal that comes together without a fuss. This John Wayne Casserole is exactly that! With minimal prep and straightforward steps, you’ll have a mouthwatering meal ready to savor in no time. Perfect for those weeknight dinner dashes!
Customizable
Feel free to unleash your inner chef! Want more cheese? Pile it on! Prefer a different spice blend? Go for it! This recipe is your canvas, inviting you to personalize it to your heart’s content, making it uniquely yours every single time.
Crowd-Pleasing
A guaranteed hit with both kids and adults. It’s always a win when a single dish can satisfy everyone at the table. This recipe strikes the perfect balance of flavor and comfort, making it a universal favorite. The combination of savory beef, tender veggies, a creamy tang, and a cheesy, biscuity base is simply irresistible.
Ingredients
Here’s the magic of this casserole—it’s made with just a few pantry staples, but the result is so much more than the sum of its parts. Let’s break it down:
Refrigerated Biscuits
The surprisingly delightful base of this casserole. They bake up into a soft, fluffy foundation that soaks up all the delicious flavors above.
Ground Beef
The hearty, savory core of the casserole, browned and seasoned to perfection, offering a robust flavor that everyone loves.
Taco Seasoning
The secret to that Tex-Mex flair! This packet of seasoning infuses the ground beef with a delicious blend of spices, bringing warmth and depth.
Onion
Diced and sautéed, adding an aromatic sweetness and savory depth to the beef mixture.
Bell Peppers
Colorful and crisp, typically green or red, these add a fresh vegetable crunch and mild sweetness to the savory layers.
Tomatoes
Freshly sliced or diced, providing a juicy, slightly acidic contrast that brightens the rich flavors of the casserole.
Sour Cream
A key component of the creamy top layer, offering a cool, tangy richness that balances the other bold ingredients.
Mayonnaise
Adds an extra layer of creaminess and savory depth to the sour cream mixture, making it incredibly luscious.
Shredded Cheddar Cheese
The glorious cheesy top! This melts into a bubbly, golden crust, adding a sharp, satisfying flavor to every forkful.
Sliced Jalapeño Peppers (Optional)
For those who like a little kick! These add a vibrant heat that perfectly complements the Southwestern flavors.
(Note: the full ingredients list, including measurements, is provided in the recipe card directly below.)

Instructions
Let’s dive into the steps to create this flavorful masterpiece:
Preheat Your Equipment
Start by preheating your oven to 350°F (175°C). This ensures even cooking and gives your dish the right texture. Lightly grease a 9×13-inch baking dish. Preheating is a small but essential step that sets the stage for success.
Prepare the Biscuit Base
Press the refrigerated biscuit dough into the bottom and slightly up the sides (about 1/2 inch) of the greased baking dish. Bake in the preheated oven for 10-15 minutes, or until lightly browned and puffed. Remove from oven and set aside, keeping the oven on.
Cook the Ground Beef
While the biscuits are baking, brown the ground beef in a large skillet over medium-high heat, breaking it into crumbles. Drain any excess fat. Stir in the taco seasoning and about 3/4 cup water (or according to package directions). Bring to a simmer, then reduce heat and cook for 5 minutes, stirring occasionally, until the liquid is mostly absorbed. Transfer the cooked beef to a bowl and wipe out the skillet.
Sauté Vegetables
In the same skillet, add a little oil if needed, then add the sliced onion and bell peppers. Cook over medium heat for about 5-7 minutes, until they begin to soften.
Prepare the Creamy Layer
In a medium bowl, combine the sour cream, mayonnaise, half of the shredded Cheddar cheese, and half of the sautéed onion and bell pepper mixture. Mix until well combined.
Assemble the Dish
Layer the browned, seasoned ground beef evenly over the pre-baked biscuit crust in the baking dish. Arrange the sliced tomatoes in a single layer over the beef. Evenly sprinkle the remaining sautéed onion and bell pepper mixture on top. If using, scatter the sliced jalapeño peppers over the vegetables. Carefully spread the creamy sour cream and mayonnaise mixture over the layers. Finally, sprinkle the remaining shredded Cheddar cheese evenly over the top. Spread everything evenly for consistent cooking. At this stage, you can also add optional toppings like shredded cheese, breadcrumbs, or fresh herbs for extra flavor.
Cook to Perfection
Bake uncovered in the preheated oven for 30-40 minutes, or until the cheese is melted and bubbly and lightly browned, and the casserole is heated through. Be sure to follow the cooking time closely to avoid overcooking or drying out the dish.
Finishing Touches
Remove from oven and let cool for 5-10 minutes. This step is crucial to let the flavors settle. It’s tempting to dig in right away, but a brief cooling period makes a big difference, allowing the layers to set slightly.
Serve and Enjoy
Serve warm and enjoy! Whether it’s paired with a side dish or served on its own, this recipe is sure to impress. Get ready for those happy sighs around the table!
Notes:
- Servings: 8
- Calories per serving: 500 (approx, varies with specific ingredients and portion size)
Preparation Time
Prep Time: 20 minutes
Cook Time: 45-55 minutes
Total Time: 65-75 minutes
How to Serve This John Wayne Casserole
This dish pairs wonderfully with various sides and accompaniments. Here are a few serving suggestions to enhance your dining experience: a simple green salad with a light vinaigrette to cut through the richness, a side of fluffy Spanish rice or quinoa, or a dollop of extra sour cream and some fresh cilantro as a garnish. It’s hearty enough to be a standalone meal, making it perfect for busy weeknights!
Additional Tips
Here are some extra tips to help you get the most out of this recipe: for easier cleanup, line your baking dish with parchment paper before greasing. Ensure your ground beef is very finely crumbled for that classic casserole texture. If you want a slightly different base, some variations use a Bisquick mix dough instead of canned biscuits. Feel free to adjust the amount of jalapeños to your preferred spice level, or omit them entirely.
FAQ’s
- Why is it called John Wayne Casserole?
The casserole is famously named after the actor John Wayne, who reportedly contributed a version of an egg and cheese casserole recipe to a cookbook for the American Cancer Society in 1979. This modern, meatier, Tex-Mex version became widely popular, often associated with his rugged, Western image. - Can I use ground turkey instead of ground beef?
Yes, ground turkey can be used as a leaner alternative. Cook it similarly to ground beef, ensuring it’s fully browned before adding seasoning. - Can I make this casserole ahead of time?
You can assemble the casserole (without baking the final cheese layer) up to 24 hours in advance. Cover and refrigerate, then add an extra 10-15 minutes to the baking time when ready to cook. - What kind of biscuits should I use?
Refrigerated flaky layer biscuits or standard dinner biscuits work well for the base. - Can I add other vegetables?
Absolutely! Diced zucchini, corn, or black beans (rinsed and drained) would be delicious additions. Add them with the bell peppers and onions. - How do I store leftovers?
Store any leftover John Wayne Casserole in an airtight container in the refrigerator for up to 3-4 days. - Can I freeze John Wayne Casserole?
Yes, you can! Bake the casserole, let it cool completely, then cover tightly with foil and plastic wrap. Freeze for up to 2-3 months. Thaw in the refrigerator overnight and reheat in the oven until warmed through. - What if I don’t like mayonnaise?
While mayonnaise adds richness, you can substitute it with more sour cream or plain Greek yogurt for a tangier, lighter creamy layer. - Can I use canned diced tomatoes with green chilies (Rotel)?
Yes, many recipes use Rotel for added flavor and convenience. Drain them well before adding to avoid excess moisture. - How can I make the biscuit crust crispier?
Ensure your oven is fully preheated, and you can bake the biscuits for a slightly longer period initially until they are a deeper golden brown before adding the layers.
Conclusion
There you have it—your ticket to a truly delightful meal that’s as simple as it is satisfying. This John Wayne Casserole is more than just a recipe; it’s a canvas for your culinary creativity, a budget-friendly superstar, and a guaranteed crowd-pleaser that will have everyone asking for seconds. So go on, gather your ingredients, turn on your oven, and get ready to create some delicious memories. Happy cooking, my friend, and enjoy every comforting bite!
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John Wayne Casserole
- Prep Time: 20 minutes
- Cook Time: 40-55 minutes
- Total Time: 1 hour – 1 hour 15 minutes
- Yield: 8–10 servings 1x
- Category: Main Course, Casserole
- Method: Baking
- Cuisine: American, Tex-Mex
Description
The John Wayne Casserole is a hearty, Tex-Mex inspired comfort food dish named after the iconic actor. It typically features a base of biscuit dough, layers of seasoned ground beef, vibrant vegetables, and a creamy, cheesy topping, baked until bubbly and golden. It’s a satisfying one-pan meal perfect for feeding a crowd.
Ingredients
- 1 (16.3 ounce) can refrigerated biscuits (like Pillsbury Grands!)
- 1 pound lean ground beef (or ground turkey)
- 1 medium yellow onion, diced
- 1 red bell pepper, diced
- 1 green bell pepper, diced
- 1 (1 ounce) packet taco seasoning mix (or 2 tablespoons homemade taco seasoning)
- 3/4 cup water
- 1 (10 ounce) can Rotel diced tomatoes and green chilies, undrained (mild or original)
- 1/2 cup sour cream
- 1/2 cup mayonnaise (light or regular)
- 8 ounces shredded sharp cheddar cheese, divided (about 2 cups)
- Optional: 1 (4 ounce) can sliced jalapeño peppers, drained (for extra heat)
- Fresh cilantro or green onions, chopped, for garnish (optional)
Instructions
- Preheat oven to 350°F (175°C). Lightly grease a 9×13 inch baking dish.
- Open the can of biscuits. Press the biscuit dough into the bottom and halfway up the sides of the prepared baking dish, stretching and pinching the seams together to form an even crust.
- Bake the biscuit crust in the preheated oven for 10-15 minutes, or until lightly browned and puffy. Remove from oven and set aside, keeping the oven on.
- While the biscuit crust bakes, brown the ground beef in a large skillet over medium-high heat, breaking it up into small pieces. Drain any excess fat.
- Add the diced onion and bell peppers to the skillet with the cooked beef. Sauté for 5-7 minutes, stirring occasionally, until the vegetables are softened.
- Stir in the taco seasoning mix and 3/4 cup water. Bring to a simmer, then reduce heat and cook for 3-5 minutes, stirring, until the liquid has mostly absorbed and the meat is well seasoned.
- In a medium bowl, combine the sour cream, mayonnaise, and half (about 1 cup) of the shredded cheddar cheese. Mix well until smooth.
- Now, assemble the casserole:
- Evenly spread the cooked seasoned ground beef and vegetable mixture over the pre-baked biscuit crust in the baking dish.
- Pour the undrained can of Rotel diced tomatoes and green chilies over the beef layer.
- If using, scatter the drained sliced jalapeño peppers over the Rotel.
- Carefully spread the sour cream and mayonnaise mixture evenly over the top of the casserole.
- Finally, sprinkle the remaining 1 cup of shredded cheddar cheese over the sour cream layer.
- Bake the casserole uncovered for 30-40 minutes, or until the cheese is melted and bubbly and the edges of the biscuit crust are golden brown.
- Remove from oven and let stand for 5-10 minutes before serving. Garnish with fresh cilantro or green onions if desired.
Notes
- **Origin:** The John Wayne Casserole gained popularity after the actor John Wayne contributed a recipe to a 1979 cookbook called ‘Cooking with Love from Cara and Her Friends,’ a fundraiser for the American Cancer Society. While his original recipe was a simpler egg and cheese dish, it evolved over time into the more elaborate, Tex-Mex inspired version popular today.
- **Meat:** You can substitute ground turkey or ground chicken for the ground beef.
- **Vegetables:** Feel free to adjust the vegetables to your preference. Corn, black beans (rinsed and drained), or a different color of bell pepper can be added.
- **Spice Level:** Adjust the amount of jalapeños and type of Rotel (mild, original, hot) to control the spice level.
- **Make Ahead:** The beef and vegetable mixture can be cooked a day in advance and stored in the refrigerator. Assemble the casserole just before baking.
- **Storage:** Leftovers can be stored in an airtight container in the refrigerator for 3-4 days. Reheat in the oven or microwave.
Nutrition
- Serving Size: 1/8 to 1/10 of casserole
- Calories: 400-600 (highly variable based on specific ingredients, fat content of meat/cheese, and portion size)
- Sugar: 8-15g
- Sodium: 700-1200mg
- Fat: 25-45g
- Saturated Fat: 10-20g
- Unsaturated Fat: N/A
- Trans Fat: 0g
- Carbohydrates: 30-50g
- Fiber: 2-5g
- Protein: 25-35g
- Cholesterol: 70-120mg
Keywords: John Wayne Casserole, Beef Casserole, Biscuit Casserole, Tex-Mex, Ground Beef, Easy Dinner, Family Meal, Comfort Food